Interaction network and enrichment analysis of genes downregulated in nasopharynx carcinoma
Canned Analysis
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General Information
AccessionDCA00034291
TitleInteraction network and enrichment analysis of genes downregulated in nasopharynx carcinoma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by nasopharynx carcinoma and healthy control cells in the Microdissected nasopharyngeal carcinoma (NPC) tissues samples - stage T3N2 cell type.
Analysis URLhttp://genemania.org/#/search/human/IGHV4-31|CYAT1|IGLC7|CSTA|IGK|CCL20|IGHA2|TUBA1A|TMSB4XP8|PLAC8|UPK1B|S100P|HLA-DPB1|SPINK5|SAT1|RPS29|IGLL3P|C9orf24|AMY2B|GABRP|DHRS9|RSPH1|LCN2|TUBB4B|RPL32
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:778
Cell TypeMicrodissected nasopharyngeal carcinoma (NPC) tissues samples - stage T3N2
DO IDDOID:9261
Disease Namenasopharynx carcinoma
Organismhuman
UMLS CUIC0238301
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM312896, GSM312897, GSM312898, GSM312899, GSM312900, GSM312901, GSM312902, GSM312903, GSM312904, GSM312905
Perturbed SamplesGSM312908, GSM312936
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE12452
Gene Expression Omnibus
Nasopharyngeal carcinoma
35
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