Interaction network and enrichment analysis of genes upregulated in pancreatic cancer
Canned Analysis
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General Information
AccessionDCA00034322
TitleInteraction network and enrichment analysis of genes upregulated in pancreatic cancer
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by pancreatic cancer and healthy control cells in the PANC-1 PANCREATIC ADENOCARCINOMA CELL LINE cell type.
Analysis URLhttp://genemania.org/#/search/human/TGFBI|HSPB1|F2RL1|C15orf48|AMIGO2|ID1|CTGF|NME1|FABP5|TUBA1C|TUBA1A|ACTB|UAP1|MLLT11|GARS|SPDL1|IER3|HMOX1|TUBB2A|ITGAV|NME1-NME2|PMEPA1|PFN1|TMSB10|GNG5
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
CREEDS IDdz:798
Cell TypePANC-1 PANCREATIC ADENOCARCINOMA CELL LINE
DO IDDOID:1793
Disease Namepancreatic cancer
Organismhuman
UMLS CUIC0153463
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM590166, GSM590167, GSM590168
Perturbed SamplesGSM590169, GSM590170, GSM590171
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE23952
Gene Expression Omnibus
Transforming growth factor beta effect on Panc-1 pancreatic adenocarcinoma cell line
7
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