Interaction network and enrichment analysis of genes upregulated in urticaria
Canned Analysis
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General Information
AccessionDCA00034364
TitleInteraction network and enrichment analysis of genes upregulated in urticaria
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by urticaria and healthy control cells in the Skin cell type.
Analysis URLhttp://genemania.org/#/search/human/MT2A|THBS1|HSPA8|NAMPT|FGL2|RNU5E-1|ACTG1|STEAP4|CTSL|SOD2|LDHA|MAT2A|TIMP1|ACTB|CCL2|NCL|SRGN|EIF5AL1|HSP90AB1|ENO1|ETS2|EIF1|G3BP1|KRT14|TNFAIP6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgswaminath
CREEDS IDdz:815
Cell TypeSkin
DO IDDOID:1555
Disease Nameurticaria
Organismhuman
UMLS CUIC0029839
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1376738, GSM1376740, GSM1376742, GSM1376744, GSM1376746, GSM1376748, GSM1376749, GSM1376750, GSM1376751, GSM1376752, GSM1376753, GSM1376754
Perturbed SamplesGSM1376737, GSM1376739, GSM1376741, GSM1376743, GSM1376745, GSM1376747
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE57178
Gene Expression Omnibus
Gene Expression Profiles in Chronic Idiopathic Urticaria
7
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