Interaction network and enrichment analysis of genes upregulated in pulmonary tuberculosis
Canned Analysis
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General Information
AccessionDCA00034388
TitleInteraction network and enrichment analysis of genes upregulated in pulmonary tuberculosis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by pulmonary tuberculosis and healthy control cells in the Lung (from B6D2F1 females) - 42 days post infection cell type.
Analysis URLhttp://genemania.org/#/search/mouse/B2m|H2-Q6|Cd74|H2-K1|H2-Aa|H2-Eb1|H2-D1|Gbp11|C3|Ctss|Tgtp2|Ly6a|H2-Ab1|Cybb|Stat1|Gbp2|Lcn2|Ly6i|AW112010|Psap|Cxcl9|Gbp4|H2-Ea-ps|Lgals3bp|Rnu2-10
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:831
Cell TypeLung (from B6D2F1 females) - 42 days post infection
DO IDDOID:2957
Disease Namepulmonary tuberculosis
Organismmouse
UMLS CUIC0041327
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1165956, GSM1165957, GSM1165958, GSM1165959
Perturbed SamplesGSM1165960, GSM1165961, GSM1165962, GSM1165963, GSM1165964, GSM1165965
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48027
Gene Expression Omnibus
Pyrazinamide effect on pulmonary tuberculosis model : time course
28
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