Interaction network and enrichment analysis of genes downregulated in glioblastoma multiforme
Canned Analysis
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General Information
AccessionDCA00034453
TitleInteraction network and enrichment analysis of genes downregulated in glioblastoma multiforme
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by glioblastoma multiforme and healthy control cells in the Brain tumor tissue samples of human gliomas and normal brain - Grade:IV - Secundary tumor cell type.
Analysis URLhttp://genemania.org/#/search/human/KIAA1598|PLP1|ND2|ERMN|HSPA1A|PCDH9|MAL|TP53INP2|MOBP|HSPA2|CNDP1|CNP|PAQR6|ENPP2|OLIG1|NDRG1|CSRP1|SYS1-DBNDD2|ATP1B1|FAM107B|HBA2|AMER2|SOX2-OT|MTURN|FTH1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:863
Cell TypeBrain tumor tissue samples of human gliomas and normal brain - Grade:IV - Secundary tumor
DO IDDOID:3068
Disease Nameglioblastoma multiforme
Organismhuman
UMLS CUIC0017636
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM397659, GSM397660
Perturbed SamplesGSM397653, GSM397654, GSM397655
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15824
Gene Expression Omnibus
Glioblastoma cell lines: LN018, LN215, LN229, LN319 and BS149
35
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