Interaction network and enrichment analysis of genes upregulated in West Nile fever
Canned Analysis
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General Information
AccessionDCA00034482
TitleInteraction network and enrichment analysis of genes upregulated in West Nile fever
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by West Nile fever and healthy control cells in the Primary retinal pigment epithelial (RPE) cells cell type.
Analysis URLhttp://genemania.org/#/search/human/IFIT1|IFIT2|IFI6|MX1|DDX58|STAT1|DDX60L|RSAD2|IFI44L|USP41|GBP3|ZC3HAV1|RN7SL2|SLFN5|PARP14|IFIT3|HLA-B|HLA-C|EIF2AK2|TAP1|PNPT1|HLA-A|TRIM25|PARP9|OAS1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:874
Cell TypePrimary retinal pigment epithelial (RPE) cells
DO IDDOID:2366
Disease NameWest Nile fever
Organismhuman
UMLS CUIC0043124
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM762060, GSM762062, GSM762064, GSM762066
Perturbed SamplesGSM762061, GSM762063, GSM762065, GSM762067
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30719
Gene Expression Omnibus
West Nile virus infection effect on retinal pigment epithelium cells
7
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