Interaction network and enrichment analysis of genes upregulated in pulmonary sarcoidosis
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00034538
TitleInteraction network and enrichment analysis of genes upregulated in pulmonary sarcoidosis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by pulmonary sarcoidosis and healthy control cells in the Lungs cell type.
Analysis URLhttp://genemania.org/#/search/human/HLA-A|LYZ|HLA-DRB4|HLA-DRA|HLA-B|HLA-DRB5|MT2A|LOC100510519|CXCL9|RPL32|SCGB1A1|CTSK|HLA-C|EIF3E|HIF1A|LUM|TMSB10|RPS29|RPL21|TIMP1|UBD|HNRNPA1P10|SLC38A2|RPS5|PTGES3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:916
Cell TypeLungs
DO IDDOID:13406
Disease Namepulmonary sarcoidosis
Organismhuman
UMLS CUIC0036205
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM415386, GSM415387, GSM415388, GSM415389, GSM415390, GSM415391
Perturbed SamplesGSM415392, GSM415393, GSM415394, GSM415395, GSM415396, GSM415397
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16538
Gene Expression Omnibus
Pulmonary sarcoidosis
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.