Interaction network and enrichment analysis of genes upregulated in XBP1 expression of XBP1s, an spliced version of the protein
Canned Analysis
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General Information
AccessionDCA00034600
TitleInteraction network and enrichment analysis of genes upregulated in XBP1 expression of XBP1s, an spliced version of the protein
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between XBP1 expression of XBP1s, an spliced version of the protein cells and control cells in the splenic B cells cell type.
Analysis URLhttp://genemania.org/#/search/mouse/S100a8|S100a9|Hbb-bs|Hba-a2|Lyz2|LOC665506|Trav9d-3|Erdr1|E430024C06Rik|Ccl5|Ifitm3|Sepp1|Tyrobp|Fxyd5|Saraf|S100a4|Thy1|Cd3d|Ctla2a|Ms4a6b|Il7r|A130040M12Rik|Ngp|Selplg|Atp1b3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1507
Cell Typesplenic B cells
Gene Symbol (human)XBP1
Gene Symbol (mouse)Xbp1
Organismmouse
Perturbation Typeexpression of XBP1s, an spliced version of the protein
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM160730, GSM160731, GSM160739, GSM160860, GSM160861
Perturbed SamplesGSM160864, GSM160865, GSM160866, GSM160867, GSM160868
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6980
Gene Expression Omnibus
Multiple myeloma model
14
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