Interaction network and enrichment analysis of genes upregulated in prostate cancer
Canned Analysis
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General Information
AccessionDCA00034618
TitleInteraction network and enrichment analysis of genes upregulated in prostate cancer
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by prostate cancer and healthy control cells in the Prostate tissue (primary prostate tumor) cell type.
Analysis URLhttp://genemania.org/#/search/human/LTF|RPS26|PLA2G2A|TARP|NPY|PRAC1|SERPINA3|C1QTNF3|ALDH1A3|TSPAN1|ODC1|EPCAM|NACAP1|EEF2|ZFP36|TMEM178A|TMSB15A|MARCKSL1|RPS2|FOS|RPLP0P6|UAP1|MYBPC1|FMOD|RPS7
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:990
Cell TypeProstate tissue (primary prostate tumor)
DO IDDOID:10283
Disease Nameprostate cancer
Organismhuman
UMLS CUIC0376358
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM74875, GSM74876, GSM74877, GSM74878, GSM74879, GSM74880
Perturbed SamplesGSM74881, GSM74882, GSM74883, GSM74884, GSM74885, GSM74886, GSM74887
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3325
Gene Expression Omnibus
Prostate cancer progression
14
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