Interaction network and enrichment analysis of genes upregulated following Celecoxib treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00034742
TitleInteraction network and enrichment analysis of genes upregulated following Celecoxib treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Celecoxib treated cells and untreated control cells in the AGS cells cell type.
Analysis URLhttp://genemania.org/#/search/human/RNU1-1|TXNIP|MMP1|FTL|APOA2|REG1A|SNORD33|NQO1|COX16|CST1|SNORD13|SNORA45A|SNORA23|GDF15|RNU4-1|SNORA22|SNHG3|SLC2A1|LYZ|RMRP|NPC2|GPX2|UBB|ECH1|MBNL3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdrug:2501
Cell TypeAGS cells
Drug NameCelecoxib
DrugBank IDDB00482
Organismhuman
PubChem CID2662
SMILES IDCC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1321413, GSM1321414, GSM1321415
Perturbed SamplesGSM1321416, GSM1321417, GSM1321418
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54657
Gene Expression Omnibus
Celecoxib induced transcriptional alterations in gastric cancer cells
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.