Interaction network and enrichment analysis of genes downregulated following Ethanol treatment
Canned Analysis
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General Information
AccessionDCA00035185
TitleInteraction network and enrichment analysis of genes downregulated following Ethanol treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Ethanol treated cells and untreated control cells.
Analysis URLhttp://genemania.org/#/search/human/HBB|DEFA1B|RPL13AP5|RPL21|RPL30|RPS27|RPL41|HBA2|GYPC|RPS18|RPSA|RPL19|R3HDM4|CD74|IL7R|RPS3|HBD|PPBP|RPS15A|RPL36A|HBG2|FAIM3|NRGN|RPS24|RPL37
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2738
Drug NameEthanol
DrugBank IDDB00898
Organismhuman
PubChem CID702
SMILES IDCCO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM87870, GSM87875, GSM87903, GSM87912, GSM87940
Perturbed SamplesGSM87865, GSM87889, GSM87898, GSM87915, GSM87936, GSM87945
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3846
Gene Expression Omnibus
Blood response to various beverages: time course
7
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