Interaction network and enrichment analysis of genes downregulated following Vitamin a treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00035315
TitleInteraction network and enrichment analysis of genes downregulated following Vitamin a treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Vitamin a treated cells and untreated control cells.
Analysis URLhttp://genemania.org/#/search/rat/COX3|Pabpc4|LOC100363434|Col1a2|Col1a1|Rplp2|Rpl32-ps3|ND1|ND2|Krt5|COX2|ATP6|CYTB|COX1|Rps12|Rpl41|Col3a1|ND4|Rps16|Rpl9|Rpl23|Rpl27a|Krt14|Myh2|Tchh
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2839
Drug NameVitamin a
DrugBank IDDB00162
Organismrat
SMILES IDOC/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)\C)\C
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM3900, GSM3904, GSM3905
Perturbed SamplesGSM3902, GSM3907
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE284
Gene Expression Omnibus
Skin tumors and vitamin A supplements
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.