Interaction network and enrichment analysis of genes downregulated following Torcetrapib treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
| Accession | DCA00035325 |
| Title | Interaction network and enrichment analysis of genes downregulated following Torcetrapib treatment |
| Description | The analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Torcetrapib treated cells and untreated control cells in the H295R human adrenal carcinoma cells cell type. |
| Analysis URL | http://genemania.org/#/search/human/DCAF6|DDIT4L|PKM|DLK1|SH3KBP1|DUSP6|ND2|ZNF275|NPTX2|RPS29|SMS|SPOCK1|USMG5|PDE2A|COX2|COX3|PTPLAD1|EEF1A1P9|PI4KAP1|SERINC5|COL15A1|MYL12B|NGFRAP1|PEG10|CS |
| Upload Date | September 20, 2017 |
| Uploader | maayanlab |
Metadata
| Analysis Curator | AliDot |
| CREEDS ID | drug:3035 |
| Cell Type | H295R human adrenal carcinoma cells |
| Drug Name | Torcetrapib |
| Organism | human |
| PubChem CID | 159325 |
| SMILES ID | CCC1CC(C2=C(N1C(=O)OCC)C=CC(=C2)C(F)(F)F)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)OC |
Characteristic Direction parameters
| Gene Set | downregulated |
| Gene Set Size | 50 |
| Control Samples | GSM399572, GSM399573, GSM399574 |
| Perturbed Samples | GSM399578, GSM399579, GSM399580 |
Tools
used in the analysis
Datasets
used in the analysis
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
