Interaction network and enrichment analysis of genes upregulated following Argyrin a treatment
Canned Analysis
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General Information
| Accession | DCA00035384 |
| Title | Interaction network and enrichment analysis of genes upregulated following Argyrin a treatment |
| Description | The analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Argyrin a treated cells and untreated control cells in the MCF7 breast adenocarcinoma cells - 12 Hours cell type. |
| Analysis URL | http://genemania.org/#/search/human/ND2|SH3KBP1|COX6C|RPL36A|COX1|IER3|RPL13A|MSMO1|HSPA1A|BASP1|LDHA|SLC38A2|TMSB10|TXNIP|HSPB1|RPL34|HNRNPA1P10|RPL27|EEF2|SLC25A6|RPLP0P6|RPL12|CCNG1|RPS14P3|RPL41 |
| Upload Date | September 20, 2017 |
| Uploader | maayanlab |
Metadata
| Analysis Curator | cadimo |
| CREEDS ID | drug:3052 |
| Cell Type | MCF7 breast adenocarcinoma cells - 12 Hours |
| Drug Name | Argyrin a |
| Organism | human |
| PubChem CID | 24978550 |
| SMILES ID | CCC1C2=NC(=CS2)C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(=C)C(=O)N(CC(=O)N1)C)C)CC3=CNC4=C3C(=CC=C4)OC)CC5=CNC6=CC=CC=C65 |
Characteristic Direction parameters
| Gene Set | upregulated |
| Gene Set Size | 50 |
| Control Samples | GSM212654, GSM212661, GSM297803 |
| Perturbed Samples | GSM297801, GSM297804 |
Tools
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