Interaction network and enrichment analysis of genes downregulated following Argyrin a treatment
Canned Analysis
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General Information
| Accession | DCA00035385 |
| Title | Interaction network and enrichment analysis of genes downregulated following Argyrin a treatment |
| Description | The analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Argyrin a treated cells and untreated control cells in the MCF7 breast adenocarcinoma cells - 24 Hours cell type. |
| Analysis URL | http://genemania.org/#/search/human/HSP90AA1|KRT18|SLIRP|RPS26|PSMA4|BCAS2|HSPE1|RRM2|NME1|TUBA1C|NDUFB9|CBWD1|HMGN2|PKM|TMA7|SNRPG|NDUFAB1|H2AFZ|ODC1|TFF1|GTF3C6|RAN|PTMA|TUBB4B|NHP2 |
| Upload Date | September 20, 2017 |
| Uploader | maayanlab |
Metadata
| Analysis Curator | cadimo |
| CREEDS ID | drug:3054 |
| Cell Type | MCF7 breast adenocarcinoma cells - 24 Hours |
| Drug Name | Argyrin a |
| Organism | human |
| PubChem CID | 24978550 |
| SMILES ID | CCC1C2=NC(=CS2)C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(=C)C(=O)N(CC(=O)N1)C)C)CC3=CNC4=C3C(=CC=C4)OC)CC5=CNC6=CC=CC=C65 |
Characteristic Direction parameters
| Gene Set | downregulated |
| Gene Set Size | 50 |
| Control Samples | GSM212654, GSM212661, GSM297803 |
| Perturbed Samples | GSM212659, GSM297802, GSM297806 |
Tools
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Datasets
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