Interaction network and enrichment analysis of genes downregulated following Insulin regular treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00035397
TitleInteraction network and enrichment analysis of genes downregulated following Insulin regular treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Insulin regular treated cells and untreated control cells in the Liver cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Hsd3b5|Serpina4-ps1|Apoa1|Fabp1|Thrsp|Car3|Scd1|Ces3a|Mup3|Elovl3|Aqp8|Nudt7|Cyp4a12a|Keg1|Gpam|Mup6|Slco1a1|Me1|Fasn|Inmt|Ces1d|Hp|Ctsa|Egfr|Insig1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgaribr01
CREEDS IDdrug:3290
Cell TypeLiver
Drug NameInsulin regular
DrugBank IDDB00030
Organismmouse
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM978535, GSM978536, GSM978537, GSM978538, GSM978539
Perturbed SamplesGSM978543, GSM978544, GSM978545, GSM978546, GSM978547
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39752
Gene Expression Omnibus
Streptozotocin induced type 1 diabetes: liver
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.