Interaction network and enrichment analysis of genes upregulated following Letrozole treatment
Canned Analysis
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General Information
| Accession | DCA00035450 |
| Title | Interaction network and enrichment analysis of genes upregulated following Letrozole treatment |
| Description | The analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Letrozole treated cells and untreated control cells in the breast cancer biopsies cell type. |
| Analysis URL | http://genemania.org/#/search/human/FTL|HBB|HEBP1|APMAP|TCEAL4|DBI|RPLP1|HLA-DRB1|COL1A2|GPNMB|HLA-DRB4|HBA2|UGT2B28|EIF3H|CRABP2|MGST3|VIM|NGFRAP1|FABP4|CD24|CARTPT|SDCBP|RPL13AP5|RPL9|FTH1 |
| Upload Date | September 20, 2017 |
| Uploader | maayanlab |
Metadata
| Analysis Curator | AliDot |
| CREEDS ID | drug:3097 |
| Cell Type | breast cancer biopsies |
| Drug Name | Letrozole |
| DrugBank ID | DB01006 |
| Organism | human |
| PubChem CID | 3902 |
| SMILES ID | C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3 |
Characteristic Direction parameters
| Gene Set | upregulated |
| Gene Set Size | 50 |
| Control Samples | GSM125123, GSM125125, GSM125127, GSM125129, GSM125131, GSM125133, GSM125135, GSM125137, GSM125139, GSM125141, GSM125143, GSM125145, GSM125147, GSM125149, GSM125151, GSM125153, GSM125155, GSM125157, GSM125159, GSM125161, GSM125163, GSM125165, GSM125167, GS |
| Perturbed Samples | GSM125124, GSM125126, GSM125128, GSM125130, GSM125132, GSM125134, GSM125136, GSM125138, GSM125140, GSM125142, GSM125144, GSM125146, GSM125148, GSM125150, GSM125152, GSM125154, GSM125156, GSM125158, GSM125160, GSM125162, GSM125164, GSM125166, GSM125168, GS |
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