Interaction network and enrichment analysis of genes downregulated following Streptozocin treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00035705
TitleInteraction network and enrichment analysis of genes downregulated following Streptozocin treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Streptozocin treated cells and untreated control cells in the Islets of Balb/c mice cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Ins2|Ins1|Sepp1|Gcg|Iapp|Serpini2|1810028F09Rik|Hbb-bs|Reg1|Rnase1|Rps12|Amy2a4|Cela3a|Pnlip|Gp2|Zg16|Prss2|Cela2a|Cpb1|Cel|Cela1|Sycn|LOC100503721|2210010C04Rik|Cpa2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjustinenoel
CREEDS IDdrug:3248
Cell TypeIslets of Balb/c mice
Drug NameStreptozocin
DrugBank IDDB00428
Organismmouse
PubChem CID29327
SMILES IDCN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM936823, GSM936824, GSM936825
Perturbed SamplesGSM936826, GSM936827
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE38215
Gene Expression Omnibus
Streptozotocin effect on pancreas of offspring of protein-restricted dams
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.