Interaction network and enrichment analysis of genes downregulated following Mycophenolic acid treatment
Canned Analysis
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General Information
AccessionDCA00035811
TitleInteraction network and enrichment analysis of genes downregulated following Mycophenolic acid treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Mycophenolic acid treated cells and untreated control cells in the No Data cell type.
Analysis URLhttp://genemania.org/#/search/human/IGHA2|RPS23|RPL36A|CYAT1|HBA2|RLIM|RPL3|EIF3L|RPL11|PPBP|RPL21|HNRNPA1P10|RPL30|RPL39|EEF1B2|RPL19|RPS3|HBB|RPS29|CCL5|PFN1|RPL13A|PABPC1|RPL37|RPLP0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgswaminath
CREEDS IDdrug:3302
Cell TypeNo Data
Drug NameMycophenolic acid
DrugBank IDDB01024
Organismhuman
PubChem CID446541
SMILES IDCC1=C(C(=C(C2=C1COC2=O)O)CC=C(C)CCC(=O)O)OC
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM365306, GSM365308, GSM365310, GSM365312, GSM365314
Perturbed SamplesGSM365307, GSM365309, GSM365311, GSM365313, GSM365315
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE14630
Gene Expression Omnibus
Effect of Mycophenolic Acid on renal transplant recipients
7
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