Interaction network and enrichment analysis of genes upregulated following Androstanolone treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00035940
TitleInteraction network and enrichment analysis of genes upregulated following Androstanolone treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Androstanolone treated cells and untreated control cells in the LNCaP prostate cancer cells - 16 Hours cell type.
Analysis URLhttp://genemania.org/#/search/human/PPAP2A|SLC39A10|DHCR24|DEGS1|KLK3|DBI|SLC45A3|KRT18|RLN1|TMPRSS2|C19orf48|ENDOD1|UAP1|ACSL3|PMEPA1|PRDX6|ABHD2|KCNN2|SAT1|LPAR3|FKBP5|C1orf116|AMD1|HEBP2|MPC2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3411
Cell TypeLNCaP prostate cancer cells - 16 Hours
Drug NameAndrostanolone
Organismhuman
PubChem CID10635
SMILES IDCC12CCC(=O)CC1CCC3C2CCC4(C3CCC4O)C
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM190812, GSM190815, GSM190818
Perturbed SamplesGSM190814, GSM190817, GSM190820
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7868
Gene Expression Omnibus
Prostate cancer cell line response to dihydrotestosterone: time course
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.