Interaction network and enrichment analysis of genes upregulated following Capsaicin treatment
Canned Analysis
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General Information
AccessionDCA00036390
TitleInteraction network and enrichment analysis of genes upregulated following Capsaicin treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Capsaicin treated cells and untreated control cells in the DRG neurons - 10 µM for 30 min cell type.
Analysis URLhttp://genemania.org/#/search/rat/Scd|Tpt1|Hba1|Dnajb1|Col1a2|Cst3|Abhd4|Fabp7|Hbb|Vim|Lmo4|Spp1|Dbi|Pmp22|Dag1|Zfp36|Dnaja1|Fos|Irf1|Timp1|Junb|Igfbp7|Atp5o|Emp1|Oaz1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3693
Cell TypeDRG neurons - 10 µM for 30 min
Drug NameCapsaicin
Organismrat
PubChem CID1548943
SMILES IDCC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1442972, GSM1442973, GSM1442974, GSM1442975
Perturbed SamplesGSM1442976, GSM1442977, GSM1442978, GSM1442979
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE59727
Gene Expression Omnibus
The transcriptome of TRPV1-positive sensory neurons revealed by subgroup-elimination transcriptomics
7
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