Interaction network and enrichment analysis of genes upregulated in CFTR OE
Canned Analysis
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General Information
AccessionDCA00036470
TitleInteraction network and enrichment analysis of genes upregulated in CFTR OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between CFTR OE cells and control cells in the Lungs - Homozygous transgenic cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Scgb3a1|Rpl28|Hspb1|Rps23|Alas2|Sftpd|Rpl37a|Fau|LOC544903|Hspa1b|Rps27rt|Rpl17-ps10|LOC100048552|Gnb2l1|H2-L|Neat1|Cd97|Wasf2|Prdx6|Saraf|Gpx3|Rps3a2|Rplp2|LOC100048117|Aldh1a1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1036
Cell TypeLungs - Homozygous transgenic
Gene Symbol (human)CFTR
Gene Symbol (mouse)Cftr
Organismmouse
Perturbation TypeOE
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM101260, GSM101261, GSM101264
Perturbed SamplesGSM101259, GSM101263, GSM101265
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4512
Gene Expression Omnibus
Cystic fibrosis transmembrane conductance regulator CFTR transgene overexpression effect on lungs
14
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