Interaction network and enrichment analysis of genes downregulated in UPF1 KD
Canned Analysis
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General Information
AccessionDCA00036471
TitleInteraction network and enrichment analysis of genes downregulated in UPF1 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between UPF1 KD cells and control cells in the Hela cells cell type.
Analysis URLhttp://genemania.org/#/search/human/RPS2|MT1E|RPL23A|RPL17|HNRNPA1P33|LDHB|RPS3A|RPL41|HSPD1|RPS3|NPM1|RPL5|EEF1A1|RPS24|EEF1G|RPL3|SNORA21|RPSAP58|RPL9|RPS4X|RPL12|RPL11|TGFBI|RPL4|FTH1P5
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1039
Cell TypeHela cells
Gene Symbol (human)UPF1
Gene Symbol (mouse)Upf1
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM29530, GSM29531
Perturbed SamplesGSM29532, GSM29534
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1703
Gene Expression Omnibus
RENT1 nonsense-mediated mRNA decay component knockdown
7
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