Interaction network and enrichment analysis of genes upregulated in MUC2 "missense mutation (G9492A, Accession AJ511872) resulting i
Canned Analysis
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General Information
AccessionDCA00036488
TitleInteraction network and enrichment analysis of genes upregulated in MUC2 "missense mutation (G9492A, Accession AJ511872) resulting i
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between MUC2 "missense mutation (G9492A, Accession AJ511872) resulting i cells and control cells in the Large Intestine (Distal and Proximal) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Clca6|Krt20|Usmg5|Ly6a|S100a11|S100a16|Krt19|Hist1h2ao|Agr2|AI747448|Gm6788|Actg1|Nme2|Cox7a2|Ldha|Nupr1|Pmp22|Gapdh|Plac8|Gm9790|Rps7|Krt8|Serpinb1a|Uqcrb|Hint1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCesarPrada
CREEDS IDgene:1057
Cell TypeLarge Intestine (Distal and Proximal)
Gene Symbol (human)MUC2
Gene Symbol (mouse)Muc2
Organismmouse
Perturbation Type"missense mutation (G9492A, Accession AJ511872) resulting i
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM250853, GSM250854, GSM250855
Perturbed SamplesGSM250850, GSM250851, GSM250852
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9913
Gene Expression Omnibus
Intestinal gene expression in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
14
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