Interaction network and enrichment analysis of genes upregulated in CXCL8 human IL8 transgenic
Canned Analysis
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General Information
AccessionDCA00036546
TitleInteraction network and enrichment analysis of genes upregulated in CXCL8 human IL8 transgenic
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between CXCL8 human IL8 transgenic cells and control cells in the Colon cancer tumor, CBA/C57BL/6 cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Xist|Spink3|Tff3|Erdr1|Rpl17-ps9|Spink4|Mptx1|Rps27rt|Mmp13|Hbb-bs|B2m|Sval1|Sgk1|Mt2|Spp1|Gm12191|Mgp|LOC100048552|LOC100044627|Zfp526|Rpl22l1|Rpl10a|Rpl27a|Rpl14-ps1|Rps19
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1118
Cell TypeColon cancer tumor, CBA/C57BL/6
Gene Symbol (human)CXCL8
Organismmouse
Perturbation Typehuman IL8 transgenic
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM959587, GSM959588, GSM959589
Perturbed SamplesGSM959590, GSM959591, GSM959592
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39273
Gene Expression Omnibus
Effect of transgenic human IL8 on gene expression in mouse colon cancer tumors
7
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