Interaction network and enrichment analysis of genes downregulated in NOD2 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00036549
TitleInteraction network and enrichment analysis of genes downregulated in NOD2 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between NOD2 KO cells and control cells in the Paneth cells (Ileum) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Rny3|AY761184|Hist1h4d|Rn28s1|Rmrp|Rps26|Hist2h4|Olfm4|Nupr1|Hist1h2bn|Hist1h4m|Hist1h2br|Uba52|Clca4|Defa22|Cln6|Ighv1-72|2210407C18Rik|Rps14|Ndufa4|Hmga1-rs1|Ccdc38|Lyz1|Hist1h2ao|Cps1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1120
Cell TypePaneth cells (Ileum)
Gene Symbol (human)NOD2
Gene Symbol (mouse)Nod2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1422810, GSM1422811, GSM1422812
Perturbed SamplesGSM1422813, GSM1422814, GSM1422815
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE58948
Gene Expression Omnibus
Gene expression analysis of crypt base epithelial cells from WT and Nod2-/- mice
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.