Interaction network and enrichment analysis of genes upregulated in TRAF6 shRNA
Canned Analysis
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General Information
AccessionDCA00036590
TitleInteraction network and enrichment analysis of genes upregulated in TRAF6 shRNA
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between TRAF6 shRNA cells and control cells in the TF-1 cell type.
Analysis URLhttp://genemania.org/#/search/human/ANXA1|HBD|SNORA45A|SLC38A2|SELT|RNU1-1|LIPH|ATP6V0E1|PHACTR4|TWF1|TFRC|SLC25A6|LAPTM4A|NRBP1|ARF4|SLC40A1|MPP1|LGALS1|TMBIM6|PIM1|SRGN|IDH1|TXNIP|CMPK1|RPL13AP5
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1134
Cell TypeTF-1
Gene Symbol (human)TRAF6
Gene Symbol (mouse)Traf6
Organismhuman
Perturbation TypeshRNA
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM944497, GSM944498
Perturbed SamplesGSM944499, GSM944500
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38519
Gene Expression Omnibus
Cytotoxic effects of Bortezomib in Myelodysplastic syndrome/Acute Myeloid Leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and rep...
7
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