Interaction network and enrichment analysis of genes upregulated in STAT6 KO
Canned Analysis
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General Information
AccessionDCA00036638
TitleInteraction network and enrichment analysis of genes upregulated in STAT6 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between STAT6 KO cells and control cells in the bone-marrow derived macrophages cell type.
Analysis URLhttp://genemania.org/#/search/mouse/4930481A15Rik|Vsig4|Frem2|2410124H12Rik|Gm4632|Mcpt8|D630004N19Rik|Gdpd2|4933407G14Rik|Sult1c2|Krt33b|Gip|Dcst2|Krtap2-4|Cd163|Lpo|Azgp1|Slc13a2|Sox14|Olfr288|Cd4|Cyp26a1|Cct8l1|Chst3|C79601
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1160
Cell Typebone-marrow derived macrophages
Gene Symbol (human)STAT6
Gene Symbol (mouse)Stat6
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM616130, GSM616134, GSM616138
Perturbed SamplesGSM616142, GSM616146, GSM616150
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25088
Gene Expression Omnibus
PPARg and IL-4-induced gene expression data from wild-type and STAT6 knockout mouse bone marrow-derived macrophages
7
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