Interaction network and enrichment analysis of genes upregulated in E2F4 KO
Canned Analysis
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General Information
AccessionDCA00036644
TitleInteraction network and enrichment analysis of genes upregulated in E2F4 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between E2F4 KO cells and control cells in the MEF cells cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Hmgn2-ps1|H19|Gm3601|Rps9|Hist1h2ao|Eno1b|H2afz|Tuba1a|Gm6402|Rps12|Rps11|Hspa5|Pgk1|Eif5a|Calr|Vim|Rplp0|Asns|Acat2|Rpl7|LOC630855|Mif|Cct2|Ldha|LOC100503055
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDgene:1167
Cell TypeMEF cells
Gene Symbol (human)E2F4
Gene Symbol (mouse)E2f4
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM278989, GSM278990, GSM278991, GSM278992, GSM278993, GSM278994, GSM278995, GSM278996, GSM278997, GSM278998
Perturbed SamplesGSM278999, GSM279000, GSM279001, GSM279002, GSM279003, GSM279004, GSM279005, GSM279006, GSM279007, GSM279008
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE11039
Gene Expression Omnibus
Expression Data from wild type and E2F4 null MEFs
7
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