Interaction network and enrichment analysis of genes downregulated in MYOD1 Mutation - MyoD altered at lysine residues 99, 102, and 104, ren
Canned Analysis
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General Information
AccessionDCA00036667
TitleInteraction network and enrichment analysis of genes downregulated in MYOD1 Mutation - MyoD altered at lysine residues 99, 102, and 104, ren
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MYOD1 Mutation - MyoD altered at lysine residues 99, 102, and 104, ren cells and control cells in the Embryonic fibroblasts - 24 Hours cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Gm4076|Bsg|Tmem8c|Ckb|Actc1|Myog|Tnni1|Hrc|Spg21|Bnip3|Plin3|Arl6ip5|Lamp1|Ldha|Atp5g3|Mylpf|Olfml2b|Tnnt2|Psmc3|Srp14|Ndufv3|Pfn1|Cyc1|Eno1b|Atp1b3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1180
Cell TypeEmbryonic fibroblasts - 24 Hours
Gene Symbol (human)MYOD1
Gene Symbol (mouse)Myod1
Organismmouse
Perturbation TypeMutation - MyoD altered at lysine residues 99, 102, and 104, ren
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM148422, GSM148426, GSM148427
Perturbed SamplesGSM148429, GSM148434, GSM148445
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE6487
Gene Expression Omnibus
Myogenic transcription factor MyoD mutant expression effect on embryonic fibroblast: time course
14
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