Interaction network and enrichment analysis of genes upregulated in SOCS3 Constitutive expression
Canned Analysis
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General Information
AccessionDCA00036682
TitleInteraction network and enrichment analysis of genes upregulated in SOCS3 Constitutive expression
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between SOCS3 Constitutive expression cells and control cells in the Skeletal muscles cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Mybpc1|Pdk4|Txnip|Hk2|Flnc|Slc25a4|Malat1|Chpt1|Ckm|Ankrd1|Prf1|Xirp1|Myh1|Mdh1|Tfrc|Fhl1|Ndufc2|Myh4|Mustn1|Prdx3|Uqcrb|Ucp3|Got1|Acsl1|Mylk4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1189
Cell TypeSkeletal muscles
Gene Symbol (human)SOCS3
Gene Symbol (mouse)Socs3
Organismmouse
Perturbation TypeConstitutive expression
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM426843, GSM426844, GSM426845
Perturbed SamplesGSM426840, GSM426841, GSM426842
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE17063
Gene Expression Omnibus
Suppressor of cytokine signaling 3 expression effect on skeletal muscles
7
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