Interaction network and enrichment analysis of genes downregulated in CTNNB1 beta-catenin S37A mutant
Canned Analysis
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General Information
AccessionDCA00036725
TitleInteraction network and enrichment analysis of genes downregulated in CTNNB1 beta-catenin S37A mutant
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between CTNNB1 beta-catenin S37A mutant cells and control cells in the 293T cells cell type.
Analysis URLhttp://genemania.org/#/search/human/RPL36A|RPS29|BASP1|XIST|RPL41|RPL37|RPL36|RPL4|RPL35|TRMT5|RPL34|RPL32|VIM|HMGN2|PPIA|RPS15A|RPL3|PABPC3|RPL23A|RPS5|TMSB10|UBA52|RPS25|COX6A1|UBC
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1217
Cell Type293T cells
Gene Symbol (human)CTNNB1
Organismhuman
Perturbation Typebeta-catenin S37A mutant
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM24862, GSM24863, GSM24864, GSM24865
Perturbed SamplesGSM24858, GSM24859, GSM24860, GSM24861
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE1473
Gene Expression Omnibus
Beta-catenin S37A mutant effect on gene expression
7
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