Interaction network and enrichment analysis of genes downregulated in RAD21 KD
Canned Analysis
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General Information
AccessionDCA00036919
TitleInteraction network and enrichment analysis of genes downregulated in RAD21 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between RAD21 KD cells and control cells in the ES cells cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Asns|Pou5f1|Chchd10|Zfp42|Mt2|Dppa5a|Ifitm1|Lap3|Nanog|Gm7325|Psat1|Cth|Skp1a|LOC100504949|Rpl4|G3bp2|Mylpf|Zfp526|Snrpd2|Nr0b1|Nars|Gm10260|Hmces|Lamp3|Hax1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1330
Cell TypeES cells
Gene Symbol (human)RAD21
Gene Symbol (mouse)Rad21
Organismmouse
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM589801, GSM589802, GSM589803, GSM589804
Perturbed SamplesGSM589805, GSM589806, GSM589807, GSM589808
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE23923
Gene Expression Omnibus
Expression data from Rad21 knock-down in ES cells
7
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