Interaction network and enrichment analysis of genes downregulated in TRNP1 KD
Canned Analysis
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General Information
AccessionDCA00036995
TitleInteraction network and enrichment analysis of genes downregulated in TRNP1 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between TRNP1 KD cells and control cells in the embryonic cerebral cortex cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Rny3|Hist1h4d|Hist1h4m|Snord32a|Rn28s1|Neurod6|Hist1h2bm|Snord49b|Rps28|H1f0|Bcl11a|Hist2h2ab|Scarna17|Hist1h2br|Rps27rt|Hist2h4|Hist1h2bn|Neurog2|Rs5-8s1|Rn7sk|Tubb5|Rps16-ps2|Hist1h1b|Nfib|Hist1h3i
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1375
Cell Typeembryonic cerebral cortex
Gene Symbol (human)TRNP1
Gene Symbol (mouse)Trnp1
Organismmouse
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM997203, GSM997204, GSM997205
Perturbed SamplesGSM997207, GSM997208, GSM997209
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40582
Gene Expression Omnibus
TRNP1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate
7
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