Interaction network and enrichment analysis of genes upregulated in DUX4 OE
Canned Analysis
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General Information
AccessionDCA00037070
TitleInteraction network and enrichment analysis of genes upregulated in DUX4 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between DUX4 OE cells and control cells in the primary myoblasts cell type.
Analysis URLhttp://genemania.org/#/search/human/TRIM51|ZSCAN4|TRIM43B|KHDC1L|CCNA1|MBD3L5|LOC729458|RFPL3|PNP|TRIM48|MBD3L4|ODC1|MBD3L2|SLC2A3|PRAMEF9|MBD3L3|PRAMEF4|NXF1|RFPL2|PRAMEF12|DNAJA1|PRAMEF5|TRIM49D1|TRIM49D2P|SRSF8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1429
Cell Typeprimary myoblasts
Gene Symbol (human)DUX4
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM836025, GSM836026, GSM836027, GSM836028
Perturbed SamplesGSM836021, GSM836022
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE33799
Gene Expression Omnibus
DUX4 activates germline genes, retroelements and immune-mediators: Implications for facioscapulohumeral dystrophy
14
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