Interaction network and enrichment analysis of genes downregulated in NR4A2 OE
Canned Analysis
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General Information
AccessionDCA00037073
TitleInteraction network and enrichment analysis of genes downregulated in NR4A2 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between NR4A2 OE cells and control cells in the HB-1 cells cell type.
Analysis URLhttp://genemania.org/#/search/human/IFITM2|IFITM1|IFITM3|ATF4|IGFBP4|DDIT4|COL5A2|MT1HL1|ID3|CEBPB|MT2A|LBR|SERPINH1|MT1E|HSPB1|MT1X|PSAT1|RNPEP|PHGDH|TMEM189-UBE2V1|MEIS2|SLC38A2|TKT|SAT1|SLC7A5
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1431
Cell TypeHB-1 cells
Gene Symbol (human)NR4A2
Gene Symbol (mouse)Nr4a2
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1412233, GSM1412235, GSM1412237
Perturbed SamplesGSM1412234, GSM1412236, GSM1412238
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE58475
Gene Expression Omnibus
Identification of genes modulated by Nurr1 overexpression
7
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