Interaction network and enrichment analysis of genes upregulated in CTNNB1 KO
Canned Analysis
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General Information
AccessionDCA00037132
TitleInteraction network and enrichment analysis of genes upregulated in CTNNB1 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between CTNNB1 KO cells and control cells in the embryonic pancreas, day E14.5 cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Cela3a|Myh8|Cela3b|Cpb1|Cpa3|AI506816|Ins2|BC003331|Rbm45|Try5|Ear2|Cela2a|Cldn11|Gm10334|Pdia2|Amy2a4|Serpina1a|Rnase1|BC023969|Dpt|Hdc|Adi1|C920025E04Rik|Itga6|Aqp4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1462
Cell Typeembryonic pancreas, day E14.5
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM177400, GSM177401
Perturbed SamplesGSM177393, GSM177397, GSM177398, GSM177399
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7430
Gene Expression Omnibus
Investigate the role of Wnt/beta-catenin signaling in development of the exocrine pancreas
7
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