Interaction network and enrichment analysis of genes upregulated in ZFX KO
Canned Analysis
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General Information
AccessionDCA00037146
TitleInteraction network and enrichment analysis of genes upregulated in ZFX KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between ZFX KO cells and control cells in the Bone marrow progenitors (c-Kit +) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Pf4|Mmp8|Ppbp|Thbs1|Gm5483|Hbb-b2|Mt2|Hbb-bt|Lyz2|Npy|BC117090|Psap|Itgb3|Mmp9|Wfdc17|Crip1|Gpr56|Ifitm1|Plek|Stfa3|Lpl|Stfa2l1|Il1f9|Timp3|Gclm
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1472
Cell TypeBone marrow progenitors (c-Kit +)
Gene Symbol (human)ZFX
Gene Symbol (mouse)Zfx
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1265778, GSM1265782, GSM1265786
Perturbed SamplesGSM1265779, GSM1265783, GSM1265787
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52416
Gene Expression Omnibus
Effect of genetic Zfx deletion on Myc induced gene expression in bone marrrow myeloid progenitors
7
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