Interaction network and enrichment analysis of genes upregulated in PARP2 KO
Canned Analysis
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General Information
AccessionDCA00037150
TitleInteraction network and enrichment analysis of genes upregulated in PARP2 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between PARP2 KO cells and control cells in the sorted Ter119+CD71+ bone marrow cells cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Nutf2-ps1|Scarna17|Hsp90ab1|Ccng1|Rnasek|Cox6b2|Hsp90aa1|Gstp1|Ypel4|Xpo7|Cd81|Car1|Ost4|Trp53inp1|Snord16a|Cdkn1a|Sord|Uba52|Aldh1a1|Gm8580|Mgst3|Rps26|Polr2l|Atp5g1|Hspd1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1474
Cell Typesorted Ter119+CD71+ bone marrow cells
Gene Symbol (human)PARP2
Gene Symbol (mouse)Parp2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1325331, GSM1325332
Perturbed SamplesGSM1325333, GSM1325334
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE54864
Gene Expression Omnibus
Parp-2 is required for efficient erythropoiesis in mice by limiting replicative stress in erythroid progenitors
7
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