Interaction network and enrichment analysis of genes upregulated in TFAP2C KD
Canned Analysis
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General Information
AccessionDCA00037192
TitleInteraction network and enrichment analysis of genes upregulated in TFAP2C KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between TFAP2C KD cells and control cells in the skin (embryonic day 16.5 mouse) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Gpx3|Krtap13|2310034C09Rik|2310057N15Rik|Lce3f|Krt77|Hspb1|Krt10|Krtdap|Kxd1|LOC100048117|Gm4076|Rps3a2|BC100530|Gm5805|Dmkn|Hba-a2|Psapl1|Gm6788|Rpl26|Rps2|Rpl27a|Rps6-ps4|LOC100044627|Krt1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1498
Cell Typeskin (embryonic day 16.5 mouse)
Gene Symbol (human)TFAP2C
Gene Symbol (mouse)Tfap2c
Organismmouse
Perturbation TypeKD
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM257174, GSM257175, GSM257176
Perturbed SamplesGSM257171, GSM257172, GSM257173
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10175
Gene Expression Omnibus
Transcription factor AP-2 gamma mutation effect on the embryonic skin
7
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