Interaction network and enrichment analysis of genes downregulated in PIK3CA Mutation
Canned Analysis
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General Information
| Accession | DCA00037199 |
| Title | Interaction network and enrichment analysis of genes downregulated in PIK3CA Mutation |
| Description | The analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between PIK3CA Mutation cells and control cells in the Analysis of estrogen receptor α-positive (ERα+) breast tumors cell type. |
| Analysis URL | http://genemania.org/#/search/human/COX2|CPB1|NPY1R|RPL30|IGHV4-31|SLC39A6|DCAF6|ISG15|ND2|YWHAZ|HSPA1A|COX1|SNHG6|HSPA8|MT2A|FTL|S100A9|COX6C|AGR3|PLAT|PSAP|MIEN1|HSPB1|CEACAM6|MT1E |
| Upload Date | September 20, 2017 |
| Uploader | maayanlab |
Metadata
| Analysis Curator | VICENTE |
| CREEDS ID | gene:1502 |
| Cell Type | Analysis of estrogen receptor α-positive (ERα+) breast tumors |
| Gene Symbol (human) | PIK3CA |
| Gene Symbol (mouse) | Pik3ca |
| Organism | human |
| Perturbation Type | Mutation |
Characteristic Direction parameters
| Gene Set | downregulated |
| Gene Set Size | 50 |
| Control Samples | GSM547768, GSM547769, GSM547770, GSM547771, GSM547776, GSM547779, GSM547780, GSM547781, GSM547782, GSM547784, GSM547785, GSM547786, GSM547787, GSM547788, GSM547789, GSM547790, GSM547791, GSM547793, GSM547795, GSM547796, GSM547797, GSM547798, GSM547801, GS |
| Perturbed Samples | GSM547772, GSM547773, GSM547774, GSM547775, GSM547777, GSM547778, GSM547783, GSM547792, GSM547794, GSM547799, GSM547800, GSM547806, GSM547807, GSM547809 |
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