Interaction network and enrichment analysis of genes downregulated in JUN Overexpression of a dominant negative form
Canned Analysis
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General Information
AccessionDCA00037203
TitleInteraction network and enrichment analysis of genes downregulated in JUN Overexpression of a dominant negative form
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between JUN Overexpression of a dominant negative form cells and control cells in the Liver tissue cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Scd1|Cyp3a41b|Zbed5|Inmt|Cyp2c70|Wfdc21|Cyp2c68|Sult2a2|Plin2|Hbb-bs|Hist1h2br|Orm1|Rps26|Sqstm1|Cyp2c29|Slc25a47|E430024C06Rik|Hist1h2bc|Mt2|Rps29|Oaz1-ps|Neat1|Cd5l|Chchd10|Cd81
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1505
Cell TypeLiver tissue
Gene Symbol (human)JUN
Gene Symbol (mouse)Jun
Organismmouse
Perturbation TypeOverexpression of a dominant negative form
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM157850, GSM157857, GSM157858, GSM157859, GSM157860
Perturbed SamplesGSM157861, GSM157862, GSM157863, GSM157864, GSM157865
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE6850
Gene Expression Omnibus
Dominant negative cJun effect on apolipoprotein E deficient livers
7
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