Interaction network and enrichment analysis of genes upregulated in MN1 reotrviral delivery of MN1 or MN1VP16 fusion for transcriptional
Canned Analysis
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General Information
AccessionDCA00037288
TitleInteraction network and enrichment analysis of genes upregulated in MN1 reotrviral delivery of MN1 or MN1VP16 fusion for transcriptional
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between MN1 reotrviral delivery of MN1 or MN1VP16 fusion for transcriptional cells and control cells in the C57BL/6J GFP+ bone marrow cells transduced with viral vector cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Tmsb4x|Fos|Ly6c2|B2m|Hp|Lyz2|Mpo|Plac8|Ctss|Tyrobp|Alox5ap|Mpeg1|Cd52|Dusp1|Camp|Ifitm3|Prtn3|F13a1|H2-L|Plbd1|S100a9|Chil4|Arhgdib|LOC100504949|Lcn2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1559
Cell TypeC57BL/6J GFP+ bone marrow cells transduced with viral vector
Gene Symbol (human)MN1
Gene Symbol (mouse)Mn1
Organismmouse
Perturbation Typereotrviral delivery of MN1 or MN1VP16 fusion for transcriptional
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1185232, GSM1185233
Perturbed SamplesGSM1185234, GSM1185235
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE48819
Gene Expression Omnibus
Gene expression changes induced by overexpression of MN1 and MN1VP16 in murine bone marrow cells
7
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