Interaction network and enrichment analysis of genes downregulated in ETS2 KD
Canned Analysis
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General Information
AccessionDCA00037289
TitleInteraction network and enrichment analysis of genes downregulated in ETS2 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between ETS2 KD cells and control cells in the H441 cell type.
Analysis URLhttp://genemania.org/#/search/human/ERO1L|SLC5A3|ELOVL1|SLC34A2|TNFRSF12A|LYPLA1|TMEM184C|SFTPA2|THBS1|DCAF12|WSB1|RDX|LAPTM4A|DCBLD2|IL6ST|MRPS6|ICAM1|KIF20A|H1F0|GPRC5A|MAPK1|OAZ1|TAF9B|MUC21|CHCHD3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaayan
CREEDS IDgene:156
Cell TypeH441
Gene Symbol (human)ETS2
Gene Symbol (mouse)Ets2
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1062875, GSM1062876, GSM1062877
Perturbed SamplesGSM1062878, GSM1062879, GSM1062880
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE43459
Gene Expression Omnibus
V-ets erythroblastosis virus E26 oncogene homolog 2 knockdown effect on lung cancer cells
19
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