Interaction network and enrichment analysis of genes upregulated in BMPR1A KO
Canned Analysis
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General Information
AccessionDCA00037334
TitleInteraction network and enrichment analysis of genes upregulated in BMPR1A KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between BMPR1A KO cells and control cells in the ES cells (N2B27 media) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Xist|Zscan4f|Xlr5b|Gm4340|Xlr3b|Mir675|H19|Nxf3|Mirg|Xlr4a|Mir382|Gm5662|Mir377|Nnat|Rian|AF357355|Mir300|Snord116l2|Mir679|Mir380|Slit3|Meg3|Prph|Ano3|Efhc2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1623
Cell TypeES cells (N2B27 media)
Gene Symbol (human)BMPR1A
Gene Symbol (mouse)Bmpr1a
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1168402, GSM1168403, GSM1168404
Perturbed SamplesGSM1168405, GSM1168406, GSM1168407
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48092
Gene Expression Omnibus
Profile of Bmpr1a-/- embryonic stem cells in ESC media and N2B27
14
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