Interaction network and enrichment analysis of genes downregulated in BMI1 OE
Canned Analysis
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General Information
AccessionDCA00037339
TitleInteraction network and enrichment analysis of genes downregulated in BMI1 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between BMI1 OE cells and control cells in the ES cells (EB differentiation) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Rpl18a|Rps15|Eif3f|Rpl11|Fth1|Rplp0|Mdk|Vim|Rpl38|Cdh11|Ftl2|Erdr1|Rps23|Itm2a|Eif4a1|Ftl1|Apoe|Gm10260|LOC100048117|Rps8|Pkm|Rps2-ps6|Fau|Eno1b|Ifitm2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1644
Cell TypeES cells (EB differentiation)
Gene Symbol (human)BMI1
Organismmouse
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM523997, GSM523998
Perturbed SamplesGSM523995, GSM523996
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20958
Gene Expression Omnibus
Polycomb repressive complex 1 protein Bmi1 transduced CCE embryonic stem cells and differentiated embryoid body samples
14
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