Interaction network and enrichment analysis of genes downregulated in EP300 KD
Canned Analysis
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General Information
AccessionDCA00037501
TitleInteraction network and enrichment analysis of genes downregulated in EP300 KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between EP300 KD cells and control cells in the hippocampus cell type.
Analysis URLhttp://genemania.org/#/search/mouse/LOC100505062|LOC100505027|Cox8b|E330037M01Rik|2900064B16Rik|D030041H20Rik|3110047M12Rik|Mal2|Samd12|Mpeg1|Cbln4|Xlr4a|BB211804|1700091H14Rik|Mical1|Grp|C130079B09Rik|LOC100504050|D130084N16Rik|D1Ertd564e|D430013B06Rik
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1746
Cell Typehippocampus
Gene Symbol (human)EP300
Gene Symbol (mouse)Ep300
Organismmouse
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM458550, GSM458551, GSM458552
Perturbed SamplesGSM458547, GSM458548, GSM458549
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE18383
Gene Expression Omnibus
p300 genetic reduction model of Rubinstein-Taybi syndrome: hippocampus
7
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