Interaction network and enrichment analysis of genes upregulated in NCSTN KD
Canned Analysis
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General Information
AccessionDCA00037508
TitleInteraction network and enrichment analysis of genes upregulated in NCSTN KD
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between NCSTN KD cells and control cells in the HEK293 cell type.
Analysis URLhttp://genemania.org/#/search/human/VIM|SNAR-A1|FTL|MYL6|TRMT5|SQSTM1|H3F3A|TUBA1C|RPL6|UCHL1|HSPA8|XPNPEP3|POLE4|RPL31|UBB|CSTB|TUBB4B|FOXC1|TUBA3FP|RPS27A|RPS12|PABPC4|CDKN1A|ARL6IP1|JUND
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1749
Cell TypeHEK293
Gene Symbol (human)NCSTN
Gene Symbol (mouse)Ncstn
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1398426, GSM1398427, GSM1398428
Perturbed SamplesGSM1398423, GSM1398424, GSM1398425
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE57949
Gene Expression Omnibus
Effects of nicastrin (NCSTN) siRNA knockdown in HEK293 and HEK001 cells.
14
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