Interaction network and enrichment analysis of genes downregulated in HNF1B Over-expression - (HNF1beta A263insGG mutant)
Canned Analysis
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General Information
AccessionDCA00037511
TitleInteraction network and enrichment analysis of genes downregulated in HNF1B Over-expression - (HNF1beta A263insGG mutant)
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between HNF1B Over-expression - (HNF1beta A263insGG mutant) cells and control cells in the HEK293 embryonic kidney cells cell type.
Analysis URLhttp://genemania.org/#/search/human/RPL11|RPL9|RPS15A|RPS6|RPL36A|RPL32|RPS15|RPL7A|RPS24|OAZ1|EEF1A1|UQCRFS1|RPS8|UQCRQ|FAU|RPL36|RPS18|ATP5A1|NCL|RHOA|RAN|SOD1|ATF4|RPSA|PRMT1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1750
Cell TypeHEK293 embryonic kidney cells
Gene Symbol (human)HNF1B
Gene Symbol (mouse)Hnf1b
Organismhuman
Perturbation TypeOver-expression - (HNF1beta A263insGG mutant)
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM74421, GSM74423
Perturbed SamplesGSM74420, GSM74422
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3308
Gene Expression Omnibus
Hepatocyte nuclear factor 1beta mutant overexpression effect on embryonic kidney cells
21
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