Interaction network and enrichment analysis of genes downregulated in TRB Stimulation ( β-chain (aVβ5) antibody)
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00037525
TitleInteraction network and enrichment analysis of genes downregulated in TRB Stimulation ( β-chain (aVβ5) antibody)
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between TRB Stimulation ( β-chain (aVβ5) antibody) cells and control cells in the Thymocytes (CD4+CD8+ double positive) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Cd8b1|Hist1h2ao|Rmnd5a|Dntt|Thy1|Rps11|Satb1|Cd8a|Tcf12|Anxa2|Cd164|Endou|H3f3b|Atl2|Cyb5a|H2-T9|Clk3|Gtf2h4|Saraf|Rpl23a|Cd4|Cdca7|Jund|Ets2|Btg2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1756
Cell TypeThymocytes (CD4+CD8+ double positive)
Gene Symbol (human)TRB
Organismmouse
Perturbation TypeStimulation ( β-chain (aVβ5) antibody)
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM24449, GSM24452
Perturbed SamplesGSM24451, GSM24454
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1448
Gene Expression Omnibus
Thymocyte response to anti-T cell receptor antibody stimulation
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.